Curated literature for prescriber reference.
A neutral summary of peer-reviewed work on compounded ketamine dosing, sublingual and intranasal pharmacokinetics, and monitoring considerations. Compiled for your review — K-Spray makes no efficacy or off-label claims.
Domains
What the literature addresses
Sublingual & oral PK
Bioavailability, time-to-peak, and dose-response data for sublingual and dissolvable oral ketamine.
Intranasal PK
Comparative pharmacokinetics for intranasal racemic and S-ketamine formats.
Monitoring considerations
Vital sign monitoring, dissociation scales, and discharge criteria reported across protocols.
Disclosure
What this is — and isn't
The references shared on request are intended for licensed prescribers and are not promotional materials. K-Spray is a compound pharmacy; any clinical decision — including off-label use — remains with the prescriber. Compounded ketamine is not an FDA-approved drug product.
We do not make efficacy claims, do not promote off-label use, and do not provide patient-directed clinical guidance.
Request the literature pack
Verified prescriber accounts can request the current curated bibliography from our pharmacy liaison.